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Volume 14 - Issue 4

(25 Articles)

(P) ISSN:2078-8665

(E) ISSN:2411-7986

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2015 > Issue 2 > Volume 12

The Effect of Proteus vulgaris Sonicate fimbriae antigens in some blood parameters and humoral immune response

Basil R. F. Razook| Ikram A.A.Al-Samarrae| Haider M.A. Al-Rubaie

Abstract:

Ten local breed rabbits were divided into two equal groups (each 5 animals).The 1st group immunized by subcutaneously 100µg/animal and the 2nd by 200µg/animal of Proteus vulgaris sonicate fimbriae antigens TWBCs. Humoral immune response effects were estimated on some blood parameters (Total and differential white blood cells) and.The results were showed a decrease in the TWBCs in the first group compared with second group; Also a significant increase (P ?0.01and P?0.05 ) was recorded in the lymphocytes and monocytes ,while a significant decrease(P ?0.01) was found in the neutrophils ,but no significant alteration (P? 0.05) was recorded in eosinophils and basophiles ;Humoral immune response was showed a synchronized increased effect with increase the dose and time of the immunization .A high titer was found after 6 weeks compared with the 2nd and 4th weeks of immunization . It was concluded that the TWBCs and Humeral immune response were synchronized with the dose and time of immunization by P. vulgaris sonicate fimbriae antigens.

Keywords:

: Proteus vulgaris, fambriae antigen, humral immune response, blood parameter..

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